Tags Amazon Message To Amazon: Now that you have regular people making your home deliveries.. Maybe they should wear a Vest with AMAZON DELIVERY on it….. I almost shot a MF creeping up to my crib last night…. Just sayin.— ICE T (@FINALLEVEL) May 21, 2019 “Just sayin…thanks for the suggestion,” Clark wrote. “We MF’ing love you and our drivers. Lots of innovations coming on this and many that already exist to help you track your package and delivery on a map. Thanks for being a customer.”Contractors who deliver packages as part of Amazon Flex aren’t required to wear uniforms, but they can use something called virtual ID on their phones to confirm their identity. Lisa Lake/Getty Images Ice-T has some advice for Amazon.The rapper took to Twitter on Tuesday to blast the e-commerce giant for not making it clear who its delivery drivers are. “Message To Amazon: Now that you have regular people making your home deliveries.. Maybe they should wear a Vest with AMAZON DELIVERY on it….. I almost shot a MF creeping up to my crib last night…. Just sayin,” Ice-T tweeted. 3 Share your voice 0:55 First published May 22 at 3:14 p.m. PT.Update, 5:02 p.m.: Adds background on Amazon Flex. Now playing: Watch this: What Amazon’s one-day shipping means for you Just sayin…thanks for the suggestion. We MF’ing love you and our drivers. Lots of innovations coming on this and many that already exist to help you track your package and delivery on a map. Thanks for being a customer.— Dave Clark (@davehclark) May 21, 2019 Comments Online Amazon’s customer service account quickly responded, asking the rapper to share details about the incident on a company support page. Dave Clark, Amazon’s senior vice president of worldwide operations, also responded to Ice-T’s tweet.
Skull of Ursus deningeri. Credit: Wikipedia Citation: Researchers reconstruct mitochondrial genome of Middle Pleistocene cave bear (2013, September 10) retrieved 18 August 2019 from https://phys.org/news/2013-09-reconstruct-mitochondrial-genome-middle-pleistocene.html © 2013 Phys.org More information: Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments, PNAS, Published online before print September 9, 2013, DOI: 10.1073/pnas.1314445110 AbstractAlthough an inverse relationship is expected in ancient DNA samples between the number of surviving DNA fragments and their length, ancient DNA sequencing libraries are strikingly deficient in molecules shorter than 40 bp. We find that a loss of short molecules can occur during DNA extraction and present an improved silica-based extraction protocol that enables their efficient retrieval. In combination with single-stranded DNA library preparation, this method enabled us to reconstruct the mitochondrial genome sequence from a Middle Pleistocene cave bear (Ursus deningeri) bone excavated at Sima de los Huesos in the Sierra de Atapuerca, Spain. Phylogenetic reconstructions indicate that the U. deningeri sequence forms an early diverging sister lineage to all Western European Late Pleistocene cave bears. Our results prove that authentic ancient DNA can be preserved for hundreds of thousand years outside of permafrost. Moreover, the techniques presented enable the retrieval of phylogenetically informative sequences from samples in which virtually all DNA is diminished to fragments shorter than 50 bp. DNA fragments over time, largely because of depurination, making it hard to analyze very old samples. The fragmentation rate is temperature-based; DNA from samples recovered from permafrost tends to be less fragmented than DNA from samples found elsewhere. Recently, for example, scientists were able to reconstruct the genome of an approximately 700,000 year old horse from a sample in Canada’s Yukon Territory. Until now, however, scientists have only been able to generate sequences from non-permafrost samples about 120,000 years old or younger.Meyer and his colleagues studied a bone sample from a Middle Pleistocene cave bear (Ursus deningeri). The sample, found at Spain’s Sima de los Huesos cave site, was more than 300,000 years old. The researchers believed they could recreate the cave bear’s genome by improving the method of DNA extraction. As DNA samples age, intact sequences become smaller. However, DNA library purification techniques tend to cause the loss of DNA molecules less than 40 bp. To preserve smaller molecules, the team used a single-stranded DNA preparation method used recently in the sequencing of Neanderthal and Denisovan genomes. This method eliminates these purification steps. By combining this single-stranded method with a widely used silica-based DNA extraction technique, the researchers were able to recover and sequence DNA molecules as short as 30 bp.Meyer’s team were able to construct a phylogeny of cave bears, determining that Ursus deningeri diverged from the common ancestor of the Late Pleistocene cave bears Ursus spelaeus and Ursus ingressus at an early stage, to form a sister lineage.The researchers say it may be possible to sequence DNA molecules even shorter than 30 bp in the future. This will allow geneticists to reconstruct even more Middle Pleistocene genomes, including those from hominin samples at the Sima Los Huesos site, which contains the largest collection of Middle Pleistocene hominin fossils in the world. Journal information: Proceedings of the National Academy of Sciences Explore further German researchers publish full Neanderthal genome (Phys.org) —Researchers have reconstructed the mitochondrial genome of a Middle Pleistocene cave bear using a bone sample found in Spain. This is the first time anyone has reconstructed such an old genome from a sample found outside the tundra. To reproduce the genome, Matthias Meyer of the Max Planck Institute for Evolutionary Anthropology in Leipzig and his team devised a new technique for stringing together small DNA strands. In addition to recreating the genome, the team were able to reconstruct the cave bear’s phylogeny. The research appears in the Proceedings of the National Academy of Sciences. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. read more
Tympanic membrane (grey), ossicular chain (yellow, green, red), and bony inner ear (blue) of a modern human with a One-Eurocent coin for scale. Credit: A. Stoessel & P. Gunz Citation: Neanderthal middle ear structure found to be closer to modern human than apes (2016, September 27) retrieved 18 August 2019 from https://phys.org/news/2016-09-neanderthal-middle-ear-closer-modern.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Genetic testing shows Neanderthals less diverse than modern humans Journal information: Proceedings of the National Academy of Sciences Explore further More information: Alexander Stoessel et al. Morphology and function of Neandertal and modern human ear ossicles, Proceedings of the National Academy of Sciences (2016). DOI: 10.1073/pnas.1605881113AbstractThe diminutive middle ear ossicles (malleus, incus, stapes) housed in the tympanic cavity of the temporal bone play an important role in audition. The few known ossicles of Neandertals are distinctly different from those of anatomically modern humans (AMHs), despite the close relationship between both human species. Although not mutually exclusive, these differences may affect hearing capacity or could reflect covariation with the surrounding temporal bone. Until now, detailed comparisons were hampered by the small sample of Neandertal ossicles and the unavailability of methods combining analyses of ossicles with surrounding structures. Here, we present an analysis of the largest sample of Neandertal ossicles to date, including many previously unknown specimens, covering a wide geographic and temporal range. Microcomputed tomography scans and 3D geometric morphometrics were used to quantify shape and functional properties of the ossicles and the tympanic cavity and make comparisons with recent and extinct AMHs as well as African apes. We find striking morphological differences between ossicles of AMHs and Neandertals. Ossicles of both Neandertals and AMHs appear derived compared with the inferred ancestral morphology, albeit in different ways. Brain size increase evolved separately in AMHs and Neandertals, leading to differences in the tympanic cavity and, consequently, the shape and spatial configuration of the ossicles. Despite these different evolutionary trajectories, functional properties of the middle ear of AMHs and Neandertals are largely similar. The relevance of these functionally equivalent solutions is likely to conserve a similar auditory sensitivity level inherited from their last common ancestor.Press release © 2016 Phys.org There has been a change in perception of Neanderthals in recent years as archaeologists have uncovered evidence that has suggested the extinct species of human was far more capable than has been conventionally believed. They built primitive homes, for example, created jewelry and painted on walls, and now, it appears they had an ear structure that would have enabled them to use vocal communications similar to modern humans. Prior research has suggested that Neanderthals came to exist approximately 280,000 years ago and lived in much of Europe and parts of Asia—but inexplicably disappeared approximately 40,000 years ago.To learn more about the aural abilities of Neanderthals, the researchers gained access to ear bones from 14 Neanderthals that have been unearthed and then performed micro-CT scans on the ossicle (inner ear parts) to create 3-D digital models—this allowed the team to recreate the means by which the human sub-species would have responded to sound. In studying the models, the researchers discovered that there were obvious structural differences between Neanderthal and modern human inner ear workings, but they performed in functionally similar ways—more so than was seen in comparing ape inner ear workings with modern humans. This suggests that human and Neanderthal hearing got its start in our common ancestorsWhen combined with genetic research a decade ago that found the FOXP2 gene in Neanderthals associated with vocal communications and speech, these new findings suggest that Neanderthals were likely able to communicate with one another in ways that were far more advanced and sophisticated than apes or other animals. The researchers suggest that the differences in ear bone structure between modern humans and Neanderthals appears likely due to differences in brain size. (Phys.org)—A team of researchers with members from the Max Planck Institute for Evolutionary Anthropology, Jena University Hospital and University College London has taken a very close look at the middle ear structure of Neanderthals and has found that while there were some obvious differences, they appeared to be closer in structure to modern humans than apes. They have outlined their study and described their results in a paper published in Proceedings of the National Academy of Sciences. read more